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What is MDMA?
3,4-Methylenedioxymethamphetamine (MDMA) could be a synthetic drug that alters mood and perception (awareness of surrounding objects and situations). it's chemically almost like both stimulant and hallucinogenic, producing feelings of increased energy, pleasure, emotional warmth, and distorted sensory and time perception.
MDMA was initially popular within the nightclub scene and all-night dance parties ("raves"), but the drug now affects a wider range of individuals who commonly refer to the drug ecstasy or molly.
How do people use MDMA?
People who use MDMA usually take it in capsule or tablet form, although some swallow it in liquid form or snort the powder. the favored nickname Molly (slang for "molecular") often refers to the alleged "pure" crystalline powder sort of MDMA, usually sold in capsules. However, people that buy powders or capsules sold as Molly are literally getting other drugs like synthetic cathinone ("bath salts") (see "Additional risks of MDMA").
Some people take MDMA with other drugs like alcohol or marijuana.
How does MDMA affect the brain?
MDMA increases the activity of three brain chemicals:
Dopamine - produces increased energy/activity and acts within the reward system to strengthen behavior
Norepinephrine- increases pulse and vital signs, which are especially risky for people with heart and vessel problems.
Serotonin- Affects mood, appetite, sleep, and other functions. It also triggers hormones that affect arousal and confidence. the discharge of huge amounts of serotonin likely causes the emotional closeness, elevated mood, and empathy felt by those that use MDMA.
Other health effects include:
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Getting feeling of nausea
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sinew cramps
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involuntary clenching of teeth
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blurred vision
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chills
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to sweat
The effects of MDMA last for about 3 to six hours, although many users take a second dose because the effects of the primary does begin to wear off. During the week after moderate use of the drug, an individual may experience:
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irritability
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impulsivity and aggression
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depression
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sleep problems
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anxiety
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memory and spotlight problems
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decreased appetite
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Loss of interest and pleasure in sex
Some of these effects could also be thanks to the combined use of MDMA with other drugs, especially marijuana.
What are the opposite health effects of MDMA?
High doses of MDMA can affect the body's ability to manage the temperature. this will cause a rise in blood heat which will sometimes end in the liver, kidney, or coronary failure, or maybe death.
In addition, because MDMA can promote trust and closeness, its use—particularly with sildenafil (Viagra®)—may encourage unsafe sexual behavior. This increases the danger of individuals getting HIV/AIDS or hepatitis.
Additional Risks of MDMA
Adding to the risks of MDMA is that pills, capsules, or powders sold as ecstasy and believed "pure" molly may contain drugs aside from or additionally to MDMA. Most mollies confiscated by police contain additives like cocaine, ketamine, methamphetamine, over-the-counter cough medicine, or synthetic cathinone ("bath salts"). These substances are often extremely dangerous if the person doesn't know what they're taking. they will even be dangerous when combined with MDMA. people that knowingly or unintentionally mix such mixtures with other substances, like marijuana and alcohol, may put themselves at even greater risk for harmful health effects.
Is MDMA Addictive?
Research results vary on whether MDMA is addictive. Experiments have shown that animals will self-administer MDMA – a crucial indicator of substance abuse potential – although to a lesser extent than other drugs like cocaine.
Some people report symptoms of addiction, including the subsequent withdrawal symptoms:
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fatigue
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loss of appetite
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depression
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trouble concentrating
What is the importance of MDMA in medicine?
MDMA was first used as an aid in psychotherapy within the 1970s (mental disorder treatment using "talk therapy"). The drug has not been tested in clinical trials (studies using humans) or within the U.S. Approval from the Food and Drug Administration wasn't endorsed. In 1985, the US Drug Enforcement Administration labeled MDMA as an illegal drug with none recognized medicinal use. Some researchers have an interest in its value in psychotherapy when given to patients under carefully controlled conditions. MDMA is currently in clinical trials as a possible treatment aid for post-traumatic stress disorder and anxiety in unsound patients and social anxiety in autistic adults.
How Can People Get Treated for MDMA Addiction?
There are not any specific medical treatments for MDMA addiction. Some people seeking treatment for MDMA addiction have found behavioral therapy to be helpful. Scientists need more research to work out how effective this treatment option is for MDMA addiction.
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